Yongming Qu
Principal Scientist - Research& Group Leader Eli Lilly
Seminars
Wednesday 19th November 2025
speakers
9:45 am
Wednesday 19th November 2025
Driving Early Success in Diabetes & Obesity Drug Development: Choosing the Optimal Drug Candidate with Model-Based Strategy to Reduce Risk & Accelerate Go/No-Go Decisions
9:30 am
- How model-based approaches were used to enable a Multiple Ascending Dose (MAD) study to serve as an early proof of concept in diabetes/obesity drug development
- Using pharmacometrics modeling to evaluate drug behavior and guide go/no-go decisions before progressing to costly Phase 2 trials
- Real-world application: A case study illustrating how modeling accelerated candidate selection and reduced development risk