Bart Borek
Seminars
Wednesday 18th November 2026
Integrating Multimodal Evidence to Inform Trial Design & Dose Selection in Rare Disease Development
10:00 am
- Combining clinical, mechanistic, biomarker, and historical datasets to support modelinformed decision-making in rare disease programmes
- Designing development strategies when untreated baseline data is unavailable
- Building modelling frameworks that connect study design, analysis, and reporting to improve confidence in dose selection decisions
Thursday 19th November 2026
Defining the Future of MIDD: Lessons Learned, Remaining Challenges & Emerging Opportunities
4:30 pm
A moderated panel drawing on speakers from across both conference days to share honest retrospective experience of MIDD implementation.
- Where has MIDD genuinely changed a development decision, and where has it been used to validate a decision that had already been made?
- What has been the hardest internal sell for MIDD, and what argument finally worked?
- Where have you seen the field overclaim what modelling can do, and what are the consequences of that for regulatory trust?
