Raj Macha
Global Head of Pharmacometrics & Quantitative Pharmacology Sanofi
Raj Macha is Global Head of Pharmacometrics at Sanofi, where he leads the strategic application of model-based approaches to accelerate drug development and decision-making across the portfolio. With more than two decades of experience spanning Quantitative Pharmacology, Pharmacometrics, and translational medicine, he has held scientific and leadership positions at Sanofi, Merck, and Boehringer Ingelheim, driving the integration of quantitative sciences from early research through late-stage clinical development.
Seminars
Thursday 19th November 2026
It Is Not One Size Fits All: How to Customise Your MIDD Framework to the Stage, Modality, & Question in Front of You
11:00 am
- Case examples illustrating how the same organisation has used different modelling approaches at candidate selection, dose optimisation, and regulatory submission for the same programme, and how each approach was chosen based on the data available and the decision being made
- How a MIDD team that supports the full development pipeline structures the feedback loop between clinical learnings and earlier-stage modelling assumptions, and how this changes the way programmes are designed from the outset
Thursday 19th November 2026
Defining the Future of MIDD: Lessons Learned, Remaining Challenges & Emerging Opportunities
4:30 pm
A moderated panel drawing on speakers from across both conference days to share honest retrospective experience of MIDD implementation.
- Where has MIDD genuinely changed a development decision, and where has it been used to validate a decision that had already been made?
- What has been the hardest internal sell for MIDD, and what argument finally worked?
- Where have you seen the field overclaim what modelling can do, and what are the consequences of that for regulatory trust?
